This medication may well interfere with specified lab checks (such as amylase/lipase levels), possibly producing Wrong take a look at benefits. Ensure lab personnel and all of your Health professionals know you use this drug.
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Observe patients for indicators and indications of respiratory melancholy and sedation. If your affected individual is visibly sedated, Assess the cause of sedation and take into consideration delaying or omitting every day methadone dosing.
Keep track of for respiratory despair, In particular through initiation of METHADOSE or subsequent a dose maximize. The peak respiratory depressant outcome of methadone happens later, and persists for a longer time than the height pharmacologic effect, Specifically throughout the Original dosing period.
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Acute or serious bronchial asthma in an unmonitored environment or during the absence of resuscitative equipment
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Significant Allergic Reactions. Methadone may possibly result in allergic reactions, which can be major. Halt using methadone and get enable instantly In case you have any of the following indicators of a serious allergic reaction.
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Instances of serotonin syndrome, a likely life-threatening situation, are described all through concomitant usage of METHADOSE with serotonergic medicines. Discontinue METHADOSE if serotonin syndrome is suspected.